About

Our lab investigates how gene expression is regulated in the liver and how this regulation affects liver biology.

 

Using genomic, metabolic and molecular biology approaches, we study the gene regulatory networks that mediate the liver’s response to nutritional status such as fasting, ketogenic diet, iron overload etc.

 

The transcriptional networks regulating hepatic metabolism are dysregulated in various diseases, including diabetes and non alcoholic fatty liver disease (NAFLD).

Therefore, a better understanding of these networks can lead to therapeutic strategies aimed at alleviating metabolic disease. 

Fasting
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Transcription factor cooperation
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Ketogenic diet
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Iron Homeostasis
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